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Case definition

This section contains the case definitions* for Acquired Immunodeficiency Syndrome (AIDS) and Human Immunodeficiency Virus (HIV) Infection

*Source: Commission Decision of 27/09/2012 laying down case definitions for reporting communicable diseases to the Community network under Decision No 2119/98/EC of the European Parliament and of the Council

Clinical Criteria (AIDS)

Any person who has any of the clinical conditions as defined in the European AIDS case definition for:

— Adults and adolescents ≥15 years

— Children <15 years of age

Laboratory Criteria (HIV)

— Adults, adolescents and children aged ≥18 months

At least one of the following three:

— Positive result of a HIV screening antibody test or a combined screening test (HIV antibody and HIV p24 antigen) confirmed by a more specific antibody test (e.g. Western blot)

— Positive result of 2 EIA antibody test confirmed by a positive result of a further EIA test

— Positive results on two separate specimens from at least one of the following three:

— Detection of HIV nucleic acid (HIV-RNA, HIV-DNA)

— Demonstration of HIV by HIV p24 antigen test, including neutralisation assay

— Isolation of HIV

— Children aged <18 months

Positive results on two separate specimens (excluding cord blood) from at least one of the following three:

— Isolation of HIV

— Detection of HIV nucleic acid (HIV-RNA, HIV-DNA)

— Demonstration of HIV by HIV p24 antigen test, including neutralisation assay in a child ≥ 1 month of age

Epidemiological Criteria: NA

Case Classification

A. Possible case: NA
B. Probable case: NA
C. Confirmed case:
— HIV infection:
Any person meeting the laboratory criteria for HIV infection

— AIDS

Any person meeting the clinical criteria for AIDS and the laboratory criteria for HIV infection

 

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