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Epidemiological situation

 Page last updated: 22 July 2016

New developments since the last epidemiological update

On 15 July, the island of Saba in the Caribbean reported its first local mosquito-borne Zika virus transmission.

On 15 July 2016, the first suspected female-to-male sexual transmission of Zika virus was reported by the US CDC

Since 18 July, the CDC has been supporting the investigation of a new case of Zika virus infection in a Utah resident who took care of a previously infected case who died in late June. Both cases were laboratory confirmed for Zika virus infection. This new case had not travelled to any affected areas and had not had sex with someone infected with Zika. Investigators are now trying to determine how this second resident became infected.

In the USA, Florida health officials are investigating possible non-travel-related cases of Zika virus in Miami-Dade County and Broward County.

On 21 July, the media reported that the first Zika vaccine has been approved by Health Canada and the US Food and Drug Administration to begin Phase I clinical trials in humans.

In Brazil, on 21 July the Ministry of Health confirmed that further studies are needed to clarify the possible link between Zika virus and Culex mosquitoes following recent unpublished research by the Oswaldo Cruz Foundation (Fiocruz) which detected Zika virus in samples collected from Culex quinquefasciatus (the popular muriçoca or house mosquito) in the city of Recife. The preliminary results of field research identified the presence of Culex quinquefasciatus naturally infected with Zika virus in three of the 80 pools of mosquitoes analysed to date.


EU/EEA imported cases

Since week 45/2015, 18 countries (Austria, Belgium, the Czech Republic, Denmark, Finland, France, Ireland, Italy, Luxembourg, Malta, the Netherlands, Norway, Portugal, Romania, Slovenia, Spain, Sweden and the UK) have reported 1048 travel-associated Zika virus infections through The European Surveillance System (TESSy).


EU’s Outermost Regions and Territories

As of 21 July 2016:  

  • Guadeloupe: 23 330 suspected cases have been detected, an increase of 1 230 suspected cases since last week. The weekly number of cases is slightly decreasing.  
  • French Guiana: 9 090 suspected cases have been detected, an increase of 120 since last week. The weekly number of cases has been decreasing over the past three weeks.  
  • Martinique: 33 460 suspected cases have been reported, an increase of 530 since last week. The weekly number of cases is stable compared to the previous week.   
  • St Barthélemy: 270 suspected cases have been detected, an increase of 45 suspected cases since last week. The virus is still actively circulating.   
  • St Martin: 1 580 suspected cases have been detected, an increase of 160 suspected cases since last week. The weekly number of cases remains stable compared to the previous week.

Update on microcephaly and/or central nervous system (CNS) malformations potentially associated with Zika virus infection

As of 20 July 2016, microcephaly and other central nervous system (CNS) malformations associated with Zika virus infection or suggestive of congenital infection have been reported by 13 countries or territories. Brazil has reported the highest number of cases. Between October 2015 and 20 July 2016, Brazil reported 8 571 suspected cases of microcephaly and other nervous system disorders suggestive of congenital infection. This represents an increase of 120 cases since the last update; 1 709 are confirmed cases of microcephaly, 267 of which are laboratory-confirmed for Zika virus infection, according to the Ministry of Health.
In the EU, Spain (2) and Slovenia (1) reported congenital malformations associated with Zika virus infection after travel in the affected areas. Cases have also been detected in the EU’s Outermost Regions and Territories in Martinique, French Guiana and French Polynesia.
Fifteen countries and territories worldwide reported an increased incidence of Guillain-Barré syndrome (GBS) and/or laboratory confirmation of a Zika virus infection among GBS cases.


ECDC assessment

The spread of the Zika virus epidemic in the Americas is likely to continue as the vectors (Aedes aegypti and Aedes albopictus mosquitoes) are widely distributed there. The likelihood of travel-related cases in the EU is increasing. A detailed risk assessment is available here. As neither treatment nor vaccines are available, prevention is based on personal protection measures. Pregnant women should consider postponing non-essential travel to Zika-affected areas.

Table 1. Countries and territories with reported confirmed autochthonous cases of Zika virus infection in the past three months, as of 22 July 2016  

Country​ Last case since 3 months​
American Samoa Widespread transmission
Anguilla Sporadic transmission
Argentina Widespread transmission
Aruba Widespread transmission
Barbados Widespread transmission
Belize Widespread transmission
Bolivia Widespread transmission
Bonaire Widespread transmission
Brazil Widespread transmission
Cape Verde Widespread transmission
Colombia Widespread transmission
Costa Rica Widespread transmission
Curaçao Widespread transmission
Dominica Widespread transmission
Dominican Republic Widespread transmission
Ecuador Widespread transmission
El Salvador Widespread transmission
Fiji Widespread transmission
French Guiana Widespread transmission
Grenada Sporadic transmission
Guadeloupe Widespread transmission
Guatemala Widespread transmission
Guinea-Bissau Sporadic transmission
Haiti Widespread transmission
Honduras Widespread transmission
Indonesia Sporadic transmission
Jamaica Widespread transmission
Martinique Widespread transmission
Mexico Widespread transmission
Micronesia, Federated States of Widespread transmission
Nicaragua Widespread transmission
Panama Widespread transmission
Paraguay Widespread transmission
Peru Widespread transmission
Philippines Sporadic transmission
Puerto Rico Widespread transmission
Saint Lucia Widespread transmission
Saint Martin Widespread transmission
Saint Vincent and the Grenadines Widespread transmission
Saint-Barthélemy Widespread transmission
Samoa Widespread transmission
Sint Eustatius Sporadic transmission
Sint Maarten Widespread transmission
Suriname Widespread transmission
Thailand Widespread transmission
Tonga Widespread transmission
Trinidad and Tobago Widespread transmission
US Virgin Islands Widespread transmission
Venezuela Widespread transmission


Figure 1. Countries or territories with reported confirmed autochthonous cases of Zika virus infection in the past three months, as of 22 July 2016


All ECDC maps with information on countries or territories with reported confirmed autochthonous cases of Zika virus infection can be found here.



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