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Epidemiological update: Case of severe lower respiratory tract disease associated with a novel coronavirus

13 Feb 2013

On 13 February 2013, the HPA announced that one family contact of the previously-confirmed case reported on 11 February was laboratory-confirmed to be infected with the novel coronavirus (NCoV). This second case from the same family was hospitalised on 9 February with a short history of respiratory symptoms. The patient has an existing medical condition that may make him more susceptible to respiratory infections. He does not have a recent travel history, and is currently receiving intensive care treatment.

The cases have been notified through the EU alerting system for communicable diseases.

This brings the total of laboratory-confirmed cases of severe pneumonia caused by the NCoV to eleven globally (see table below).

The information available suggests human-to-human transmission of the NCoV in this family cluster.

The HPA reports that surveillance of family, close contacts of the two patients and healthcare workers treating the two patients is ongoing, as per the UK National Guidelines. None are currently presenting with symptoms consistent with nCoV.

The HPA is also following-up regarding passengers who may have been exposed while flying with the case announced on 11 February 2013 and are in contact with the airline concerned.

In light of this human-to-human transmission of the NCoV within the family cluster, ECDC is now updating its risk assessment, previously published on 7 December 2012.

Erratum. The following table was amended on 19 February 2013.


Case No.

Date of Onset

Age (years)

Sex

Probable place of infection

Date reported

Outcome Part of a cluster?

Initial Source of Information 

1

April 2012

45

F

Jordan

30/11/12

Dead yes - hospital A

WHO/IHR

2

April 2012

25

M

Jordan

30/11/12

Dead yes - hospital A

WHO/IHR

3

13/06/12

60

M

Kingdom of Saudi Arabia

20/09/12

Dead no

ProMed / Publication

4

03/09/12

49

M

Qatar/ Kingdom of Saudi Arabia

23/09/12

Alive/Hospitalised no - patient transferred to the UK

HPA/publication / publication

5

10/10/2012

45

M

Kingdom of Saudi Arabia

04/11/12

Alive no

 

ProMed / Publication

6

12/10/12

45

M

Qatar

23/11/12

Alive no - patient transferred to Germany

RKI

 

7

3-5/11/2012

31

M

Kingdom of Saudi Arabia

20/11/12

Alive yes - family A

ProMed 

8

28/10/12

39

M

Kingdom of Saudi Arabia

23/11/12

Dead yes - family A

WHO/IHR

9

October 2012

not known

M

Kingdom of Saudi Arabia

28/11/12

Dead yes - family A

WHO/IHR

10

24 /1/2013

adult

 

M

Pakistan/
Kingdom of Saudi Arabia

11/02/13

Alive/Hospitalised yes - family B

HPA

 

11

6/2/2013

not known

M

United Kingdom

12/02/13

Alive/Hospitalised yes - family B

HPA

 

 
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