New tuberculosis drug bedaquiline approved by U.S. Food and Drug Administration
On 28 December 2012, the U.S. Food and Drug Administration approved bedaquiline, a new diarylquinoline antimycobacterial drug, as part of combination therapy to treat adults with multi-drug resistant tuberculosis (MDR-TB) when other alternatives are not available.
New drug resistant form of tuberculosis reported in IndiaArchived
In a recent scientific article (Udwadia, F et al. Clin. Infect. Dis. 2011, Dec 21, Eprint) four cases of so-called total drug resistant tuberculosis (TB) were reported from India.
The use of Interferon-γ release assays for Tuberculosis Screening in International TravelersArchived
IGRAs are increasingly being considered for the diagnosis of LTBI, as a replacement to the TST, including travel medicine. As with the TST, many uncertainties remain with regard to the efficacy of the IGRAs. It is therefore essential to secure an accurate understanding of these assays‘ known efficacy, so that they be optimally used and only in context with proven effect.