Effect of introducing high-valency pneumococcal conjugate vaccines on invasive pneumococcal disease in children
This is the main finding of a recent article based on data from The Streptococcus pneumoniae Invasive Disease network (SpIDnet).
Low uptake of seasonal influenza vaccination in Europe may jeopardise capacity to protect people in next pandemic
Influenza vaccination coverage among high-risk groups has dropped in the European Region over the last seven years, and half the countries report a decrease in the number of vaccine doses available.
Assessing seasonal influenza vaccine effectiveness
On 3 December 2015, ECDC hosts a technical meeting to discuss influenza vaccine effectiveness studies and how they can best meet public health needs as well as regulatory requirements.
Early estimates of field effectiveness for the 2009 pandemic vaccine in Germany using the screening method
Pandemic influenza A(H1N1) 2009 breakthrough infections and estimates of vaccine effectiveness in Germany 2009-2010
Efficacy and safety of a recombinant hepatitis E vaccine in healthy adults: a large-scale, randomised, double-blind placebo-controlled, phase 3 trial
The efficacy and safety of a new recombinant hepatitis E vaccine (HEV 239) manufactured in China was assessed in a randomised, double-blind placebo-controlled phase 3 trial among 97,356 healthy individuals aged 16-65 years in Jiangsu province, China.
Seasonal Influenza vaccine effectiveness in young children in Europe
This study was carried out in Finland and is one of the few European studies investigating the effectiveness of trivalent inactivated influenza vaccines against laboratory-confirmed influenza A and B infections in children younger than 3 years.
Efficacy and safety of single and double doses of Ivermectin versus 7-day high dose Albendazole for chronic Strongyloidiasis
A prospective, randomized, open study was conducted in which a 7-day course of oral albendazole 800 mg daily was compared with a single dose (200 microgram/kilogram body weight) or double doses, given 2 weeks apart, of ivermectin in Thai patients with chronic strongyloidiasis.
Systematic review and meta-analysis concerning the efficacy and effectiveness of seasonal influenza vaccines – (part 1)
This is an authoritative independent evidence-based review and meta-analysis of the efficacy and effectiveness of influenza vaccines. It confines itself to trials and observational studies where diagnostic tests confirmed influenza infection as the end point.
The importance of analyses of antigenic match and monitoring influenza vaccine effectiveness
Influenza viruses pose a particular challenge for those designing vaccines for humans. Much of the protective immunity that humans have against these viruses following natural infection or vaccination is due to immunological recognition of the haemagglutinin (HA) surface glycoprotein.