Ebola treatment trial: two drugs identified as more effective
Two out of the four drugs tested in a multi-drug randomised control trial have been found more effective in treating Ebola, the World Health Organization announced on Monday. The Data and Safety Monitoring Board, an independent body that has been reviewing interim safety and efficacy data, has therefore recommended that the study be stopped and that all future patients be randomized to receive either REGN-EB3 or mAb114, in what is being considered an extension phase of the study.
Targeted testing for viral hepatitis: Europe’s persistent public health challenge
Targeted testing is an essential element of any strategy to eliminate viral hepatitis across the countries in the European Union and European Economic Area. Some preliminary monitoring results on the response to hepatitis B and C presented around World Hepatitis Day show that diagnosing chronic infections is still a challenge in the EU/EEA.
Syphilis notifications in the EU/EEA up by 70% since 2010
The number of syphilis cases has been consistently going up across Europe since 2010, mostly affecting men who have sex with men living in urban areas. In 2017, notification rates reached an all-time high in the EU/EEA countries with more than 33 000 reported cases. An in-depth ECDC study published today describes the factors behind this increase and outlines the evidence-based options for public health control of syphilis, including case finding and management as well as educational activities.
ECDC’s HEPSA preparedness self-assessment tool is now available in all EU/EEA languages
The HEPSA (Health Emergency Preparedness Self-Assessment) tool that ECDC launched in 2018 in English is now available in all EU/EEA languages. This tool aims at supporting countries in improving their level of public health emergency preparedness.
ECDC: first detected cases of extensively drug-resistant gonorrhoea threaten future treatment
Within a matter of weeks, three cases of gonorrhoea that are resistant to the recommended first line antibiotic treatment have been detected in Europe and Australia. These are the first global reports of Neisseria gonorrhoeae with high-level resistance to azithromycin and ceftriaxone resistance that also show resistance to several other vital antibiotics. At a time with limited alternatives to the current dual therapy, lack of a vaccine and insufficient surveillance capacity in some regions, these cases highlight the growing threat of drug-resistance – which could lead to untreatable gonorrhoea.
Enhancing community engagement in preparedness: Crucial for ensuring effective response
The importance of involving communities in all the phases of emergency preparedness is highlighted in the new ECDC literature review on ‘Community and institutional preparedness synergies ’.
ECDC call for epidemiologists to join its Ebola response teams in Guinea
Despite a dramatic improvement of the epidemiological situation in Guinea in 2015, the elimination of human transmission of the Ebola virus will require sustained efforts over the next few months. ECDC will continue deploying experts to Guinea to contribute to the field work related to surveillance and response activities, under the World Health Organization's Global Outbreak Alert and Response Network (GOARN) umbrella.
Epidemiological update: increase in reporting of human cases of A(H5N1) influenza, Egypt, 9 April 2015
Epidemiological update: increase in reporting of human cases of A(H5N1) influenza, Egypt
High level conference on “Ebola: From Emergency to Recovery”: response so far and planning the recovery
On March 3 2015, the European Union organised a high-level conference on the Ebola epidemic. The purpose was two-fold: first, to take stock of the ongoing emergency response and adapt it to the evolving situation on the ground, leading to eradication of the disease; second, to plan for the long term and support the recovery and resilience of the affected countries, including the development of their health systems.