Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2
This new publication from Novartis in collaboration with public health and academic researchers in Finland and the US adds to the evidence-base on how narcolepsy might have been triggered in genetically susceptible individuals.
Update on narcolepsy cases associated with Pandemrix vaccination in 2009 in the Netherlands
In November 2014, the Pharmacovigilance Centre of Netherlands (Lareb) provided an updated overview of Dutch cases of narcolepsy reported to have a link to Pandemrix.
No Serological Evidence of Influenza A H1N1pdm09 Virus Infection as a Contributing Factor in Childhood Narcolepsy after Pandemrix™ Vaccination Campaign in Finland
This is the first published study where an attempt has been made to understand the possible biological mechanisms behind development of narcolepsy following vaccination with Pandemrix™.
New Swedish Registry study confirms increased risk of narcolepsy in children and adolescents after vaccination with Pandemrix
This observational cohort study utilizing electronic health care records covering 5.8 million Swedes confirmed an increased risk of narcolepsy after vaccination with Pandemrix in children and adolescents (<
Association of receipt of Pandemrix™ and narcolepsy in children and adolescents in the UK (England)
This is the sixth EU Member State reporting an association between the development of narcolepsy and vaccination with the AS03-adjuvanted influenza A H1N1 (2009) pandemic vaccine Pandemrix.
Narcolepsy and Pandemrix Vaccine – an association in adults as well as children
In September 2010 Sweden and Finland noted a number of children had developed narcolepsy seemingly in association with having received the pandemic vaccine used almost exclusively in those countries (Pandemrix)
New ECDC technical report on “Narcolepsy in association with pandemic influenza vaccination – a multi-country European epidemiological investigation”
Results from Vaccine Adverse Event Surveillance and Communication (VAESCO) Consortium studies confirm an association between vaccination with Pandemrix® and an increased risk of narcolepsy in children and adolescents (5 to 19 years of age) in Sweden and Finland.
Report on the association between the 2009 pandemic vaccine (Pandemrix®) and narcolepsy – Republic of Ireland
Investigation of an increase in the incidence of narcolepsy in children and adolescents in 2009 and 2010 - Final Report of National Narcolepsy Study Steering Committee, Department of Health, Ireland
Association of childhood narcolepsy and cataplexy and receipt of a pandemic influenza vaccine in Finland in 2009-10 – First papers in a peer review journal
A pair of linked papers from Finland concerning the above topic, one epidemiological and the second combining both clinical and epidemiological were published on March 28th in the open access journal, PLoS One.(1,2).
Training workshop on vaccine safety for Member States, building on the experience obtained in the ECDC vaccine safety project VAESCO
On the 23-24 February, ECDC organises a workshop aimed at the Member States currently not participating in the ECDC Vaccine safety network.