Rapid Risk Assessment: Outbreak of enterovirus A71 with severe neurological symptoms among children in Catalonia, Spain, 16 June 2016
ECDC has published a rapid risk assessment due to a localised outbreak of neurological symptoms associated with enterovirus A71 (EV-A71) in Catalonia, Spain.
Most EV infections, including EV-A71, result in asymptomatic infection. Most symptomatic EV-A71 infections manifest as a self-limiting hand, foot and mouth disease and only a very small proportion of patients develop severe and life-threatening disease. The current outbreak is notable in terms of its magnitude and the severity of symptoms of the reported cases.
Epidemiological update: Fatal paediatric infections associated with Enterovirus 71 in Cambodia April-July 2012, and hand, foot and mouth disease in AsiaArchived
From April to early July 2012 an unusual number and pattern of fatalities among young children were reported by Kantha Bopa Children’s Hospital in Cambodia’s capital Phnom Penh. The patients presented with fever, respiratory distress and signs of encephalitis, and most of the children were under 3 years old.
Cambodia: fatal illness in children now linked to enterovirus 71Archived
The Cambodian Ministry of Health and the World Health Organization (WHO) are currently investigating a number of cases an undiagnosed illness that has resulted in the deaths of several children in Cambodia in the past 2 months. According to the WHO, the latest laboratory results indicate that “a significant proportion of the samples tested positive for Enterovirus 71 (EV-71), which causes hand foot and mouth disease”.
Epidemiological update on hand, foot and mouth disease in Asia, May 2012Archived
As of May 2012, Vietnam continues to see sustained high incidence of hand, foot and mouth disease (HFMD) since the beginning of the year. China, Hong Kong (China), Macao (China) and Singapore have been reporting an increase in number of cases.