Rapid progress in public health implementation of whole-genome sequencing across the EU/EEA
The EU/EEA countries are making great progress in the implementation of whole-genome sequencing (WGS) technology for outbreak investigation and surveillance. With a harmonisation of standards, this will enable exchange of WGS-derived data across the EU/EEA as prioritised in ECDC Roadmap for molecular surveillance and improve disease control and prevention in Europe.
Monitoring the use of whole-genome sequencing in infectious disease surveillance in Europe 2015–2017
The results of the third pan-EU/EEA survey presented in this report showed that by mid-2017 the vast majority of national public health reference laboratories in EU/EEA countries had access to whole genome sequencing based typing of diverse microbial pathogens for investigations of infection and drug resistance transmission.
Molecular typing of Neisseria gonorrhoeae – a study of 2013 isolates
This report describes the second molecular typing survey of N. gonorrhoeae across the EU/EEA and provides recent information on NG-MAST STs/Gs and genotypes based on WGS circulating in 21 EU/EEA Member States.
Understanding drug-resistant gonorrhoea: an ECDC whole genome sequencing study
Can whole genome sequencing illustrate changes in drug susceptibility of gonorrhoea to antimicrobials used for treatment and so help to define more effective treatment regimens? The first study of this kind within an international surveillance programme for sexually transmitted infections shows distribution of drug-resistant gonorrhoea strains across Europe.
Third Joint Workshop on AMR in Salmonella and Campylobacter
This workshop on AMR in Salmonella and Campylobacter was arranged in cooperation with the FWD Network and the EU reference laboratory for antimicrobial resistance network.
Multi-laboratory validation study of multilocus variablenumber tandem repeat analysis (MLVA) for Salmonella enterica serovar Enteritidis, 2015
Peters, T., Bertrand, S., Björkman, J.T., Brandal, L.T., Brown, D.J., Erdõsi, T., Heck, M., Ibrahem, S., Johansson, K., Kornschober, C., Kotila, S.M., Le Hello, S., Lienemann, T., Mattheus, W., Nielsen, E.M., Ragimbeau, C., Rumore, J., Sabol, A., Torpdahl, M., Trees, E., Tuohy, A., De Pinna, E.
Expert opinion on whole genome sequencing for public health surveillance
This document sets out ECDC's five year vision for using whole genome sequencing (WGS) technology within the context of its agreed strategy and roadmap for integrating typing data into EU level surveillance and cross-border outbreak assessment.
Whole genome sequencing empowers disease surveillance and outbreak investigation
In the last decade, there has been a shift from microbial genotyping to Next-Generation Sequencing technology. Whole Genome Sequencing (WGS) has transformed public health surveillance and outbreak investigations by providing more accurate pathogen identification, antimicrobial resistance profiling, transmission tracking and biological risk assessment.