Call for scientific collaboration to support genomic-based surveillance of Neisseria gonorrhoeae-antimicrobial resistance at EU-level
ECDC is looking to establish a scientific collaboration with an organisation which can perform whole genome sequencing (WGS) of Neisseria gonorrhoeae, carry out related data analyses, share results of the analyses with ECDC and the participants of the European Gonococcal Antimicrobial Surveillance Programme as well as visualise the results.
Molecular typing of Neisseria gonorrhoeae – a study of 2013 isolates
This report describes the second molecular typing survey of N. gonorrhoeae across the EU/EEA and provides recent information on NG-MAST STs/Gs and genotypes based on WGS circulating in 21 EU/EEA Member States.
Understanding drug-resistant gonorrhoea: an ECDC whole genome sequencing study
Can whole genome sequencing illustrate changes in drug susceptibility of gonorrhoea to antimicrobials used for treatment and so help to define more effective treatment regimens? The first study of this kind within an international surveillance programme for sexually transmitted infections shows distribution of drug-resistant gonorrhoea strains across Europe.
Gonococcal antimicrobial susceptibility surveillance in Europe, 2014
The surveillance of Neisseria gonorrhoeae antimicrobial susceptibility in the European Union/European Economic Area (EU/EEA) has been co-ordinated by the European Centre for Disease Prevention and Control (ECDC) since 2009.
WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014
Jacobsson, S., Golparian, D., Cole, M., Spiteri, G., Martin, I., Bergheim, T., Borrego, M.J., Crowley, B., Crucitti, T., Van Dam, A.P., Hoffmann, S., Jeverica, S., Kohl, P., Mlynarczyk-Bonikowska, B., Pakarna, G., Stary, A., Stefanelli, P., Pavlik, P., Tzelepi, E., Abad, R., Harris, S.R., Unemo, M.
Molecular epidemiological typing within the European Gonococcal Antimicrobial Resistance Surveillance Programme reveals predominance of a multidrugresistant clone
Chisholm, S.A., Unemo, M., Quaye, N., Johansson, E., Cole, M.J., Ison, C.A., van der Laar, M.J.W.
Molecular typing of Neisseria gonorrhoeae
In 2011, a pilot study was undertaken to assess the public health benefit of molecular surveillance for gonorrhoea in 21 EU/EEA countries. A total of 1 066 isolates collected under the 2010 European gonococcal antimicrobial surveillance programme were typed and 406 sequence types identified, with considerable diversity among countries.