Joint Rapid Outbreak Assessment: Multi-country outbreak of Salmonella Agona infections linked to infant formula
This document provides an assessment of the public health risk associated with a multi-country outbreak of Salmonella Agona associated with consumption of potentially contaminated infant formula from France.
Listeria surveillance: new EU-wide study reveals that most outbreaks remain undetected
More than half of the severe listeriosis cases in the European Union belong to clusters, many of which are not being picked up fast enough by the current surveillance system, suggests a new article published in Eurosurveillance. The large-scale study looked into listeriosis epidemiology through whole genome sequencing and found that this method, when implemented at EU-level, could lead to faster detection of multi-country outbreaks, saving up to 5 months of the investigations.
Monitoring the use of whole-genome sequencing in infectious disease surveillance in Europe 2015–2017
The results of the third pan-EU/EEA survey presented in this report showed that by mid-2017 the vast majority of national public health reference laboratories in EU/EEA countries had access to whole genome sequencing based typing of diverse microbial pathogens for investigations of infection and drug resistance transmission.
Rapid progress in public health implementation of whole-genome sequencing across the EU/EEA
The EU/EEA countries are making great progress in the implementation of whole-genome sequencing (WGS) technology for outbreak investigation and surveillance. With a harmonisation of standards, this will enable exchange of WGS-derived data across the EU/EEA as prioritised in the ECDC Roadmap for molecular surveillance and improve disease control and prevention in Europe.
Multi-country outbreak of Listeria monocytogenes sequence type 8 infections linked to consumption of salmon products
A multi-country outbreak of 12 listeriosis cases caused by Listeria monocytogenes sequence type (ST) 8 has been identified through whole genome sequencing (WGS) analysis in three EU/EEA countries: Denmark (6 cases), Germany (5) and France (1).
Call for scientific collaboration to support genomic-based surveillance of Neisseria gonorrhoeae-antimicrobial resistance at EU-level
ECDC is looking to establish a scientific collaboration with an organisation which can perform whole genome sequencing (WGS) of Neisseria gonorrhoeae, carry out related data analyses, share results of the analyses with ECDC and the participants of the European Gonococcal Antimicrobial Surveillance Programme as well as visualise the results.
EUSeqMyTB to set standards and build capacity for whole genome sequencing for tuberculosis in the EU
Tagliani, E., Cirillo, D.M., Ködmön, C., van der Werf, M.J.
Retrospective validation of whole genome sequencing-enhanced surveillance of listeriosis in Europe, 2010 to 2015
Walle, I.V., Björkman, J.T., Cormican, M., Dallman, T., Mossong, J., Moura, A., Pietzka, A., Ruppitsch, W., Takkinen, J., Mattheus, W., Christova, I., Maikanti-Charalampous, P., Karpíšková, R., Halbedel, S., Nielsen, E.M., Koolmeister, M., Mandilara, G., Torreblanca, R.A., Salmenlinna, S., Lecuit, M., Leclercq, A., Damjanova, I., Delappe, N., Sigmundsdóttir, G., Gattuso, A., Griškevičius, A., Ragimbeau, C., Franz, E., Brandal, L.T., Kuch, A., Borges, V., Caplan, D., Jernberg, C., Alm, E., Trkov, M., Tkacova, E., Grant, K.
ECDC strategic framework for the integration of molecular and genomic typing into European surveillance and multi-country outbreak investigations
This strategic framework document presents a proposed list of priority pathogens/diseases and outlines technical implementation options for the medium-term integration (2019–2021) of molecular/genomic typing information into EU-level surveillance and multi-country outbreak investigations.
Whole genome sequencing: new ECDC framework suggests priority diseases and implementation options
Whole genome sequencing (WGS) is a fast-moving technology, but the pace of change vary between pathogens/diseases and European Union countries. In a new report, ECDC proposes to prioritise the implementation of WGS depending on disease and public health application.