Guidance and protocol for the serological diagnosis of human infection with Bordetella pertussis

Since 2011, there have been increases in the number of cases of pertussis that have been reported in different regions of the world. Laboratory diagnosis of whooping cough is difficult due to variations in specificity and the sensitivity of different methods. This report reviews the scientific literature updates together with research to produce a guidance and protocol for the serological diagnosis of human infection with Bordetella pertussis.