Rapid risk assessment: Carbapenem-resistant Acinetobacter baumannii in healthcare settings – 8 December 2016
Carbapenem-resistant A. baumannii poses a significant threat to patients and healthcare systems. A. baumannii is the cause of serious infections in healthcare settings. The situation is exacerbated by the bacteria’s carbapenem resistance which limits treatment options and increases the risk for adverse outcomes. This risk assessment provides an overview of the epidemiological situation in Europe and describes a number of response options.
Acinetobacter baumannii is the cause of difficult-to-treat infections in healthcare settings in Europe due to its increasing resistance to antimicrobial agents, in particular the carbapenems. Outbreaks of carbapenem-resistant A. baumannii in healthcare facilities have been reported in Europe and worldwide.
Infections with carbapenem-resistant A. baumannii occur in patients with severe underlying diseases, mainly in intensive care units, and are often related to invasive procedures or indwelling devices. However, such infections are increasingly being reported in patients admitted to conventional medical and surgical wards. A. baumannii is difficult to eradicate once it has become endemic.
Recent ECDC data from the European survey on carbapenemase-producing Enterobacteriaceae (EuSCAPE) project and from the European Antimicrobial Resistance Surveillance Network (EARS-Net) confirmed that although there is already a high resistance baseline in some countries, there has been an overall increase of carbapenem-resistant A. baumannii in Europe.
These data confirm an already alarming situation that continues to worsen in many EU/EEA countries. While carbapenems traditionally were the antibiotics of choice for treatment of A. baumannii infections, resistance to these drugs has led to increased use of colistin as last-line treatment. Although still rare, resistance to colistin in A. baumannii is also increasingly being reported in Europe.
This risk assessment highlights the need of increased efforts to face this significant threat to patients and healthcare systems in all EU/EEA countries and outlines options to reduce risks through clinical management, prevention of transmission in hospitals and other healthcare settings, prevention of cross-border transmission, and improvement of preparedness of EU/EEA countries.
Rapid risk assessment: Regional outbreak of New Delhi metallo-betalactamase-producing carbapenem-resistant Enterobacteriaceae, Italy, 2018–2019
4 Jun 2019 - A large outbreak of New Delhi metallo-beta-lactamase (NDM)-producing carbapenem-resistant Enterobacteriaceae (CRE) has been reported from the Tuscany region in Italy. Between November 2018 and May 2019, seven Tuscan hospitals notified a total of 350 cases.
Rapid risk assessment: Outbreak of VIM-producing carbapenem-resistant Pseudomonas aeruginosa linked to medical tourism to Mexico
11 Mar 2019 - This outbreak of Verona integron-encoded metallo-beta-lactamase-producing carbapenem-resistant Pseudomonas aeruginosa (VIM-CRPA) surgical site infections, related to invasive procedures performed in healthcare facilities in Tijuana, Baja California, Mexico, highlights the risks associated with medical tourism for patients and healthcare systems in the countries of origin.
Rapid risk assessment: Multidrug-resistant Staphylococcus epidermidis
8 Nov 2018 - This rapid risk assessment addresses the public health risk associated with a previously unrecognised international spread of near pandrug-resistant strains of S. epidermidis as a cause of infection in several countries including EU Member States.