Globally, as of 9 August, 19 cases of polio due to wild poliovirus type 1 (WPV1) and 223 cases due to circulating vaccine derived poliovirus (cVDPV) have been reported this year. In 2022, the cVDPV cases have been reported in 15 countries, with 93% of the cases attributed to cVDPV type 2 (cVDPV2).
Polio is an infectious disease mostly contracted by children. One in two hundred people develop incurable paralysis after infection. In 1955, a vaccine was invented and was introduced on a wide scale. Thanks to global efforts, polio was eliminated from the Western Hemisphere by 1994, and has greatly decreased worldwide.
This document summarises evidence from studies included in the licensing file of HPV vaccines together with postlicensure, peer-reviewed data and analysis where available. This guidance does not address the safety of HPV vaccines observed during the pre- and post-licensing period.