Artemisinin resistance in falciparum malaria has emerged in western Cambodia exactly where chloroquine resistance arose 50 years ago. Similarly to the resistance to chloroquine that spread to Africa, the experts are wondering whether artemisinin resistance will spread as widely. In such a case the consequences would be disastrous.
The authors describe a case of imported Plasmodium knowlesi infection in a French tourist acquired in Thailand. The patient had spent a three month beach holiday on the west coast of Thailand including a one month stay on the Island of Ko Payam.
Using surveillance data obtained from 21,888 imported Plasmodium falciparum cases in France during 1996-2003, factors independently associated with severe malaria (832 cases; ≈3.8%) were older age, European origin, travel to eastern Africa, absence of chemoprophylaxis, initial visit to a general practitioner, time to diagnosis of 4 to 12 days, and diagnosis during the fall-winter season.
This study describes the outcome of 25 travellers with severe malaria who returned from malaria-endemic regions and were treated at 7 centres in Europe with intravenous artesunate. Among these 25 patients, one child and 24 adults (mean ± SD age 44.1 ± 16.1 years), 10 patients received the dosing regimen for artesunate initially recommended by WHO and 11 received artesunate, 2.4 mg/kg/dose.
ECDC was pleased that the Government of Romania extended an invite to meet health care workers who are working with the Roma population. ECDC Director, Marc Sprenger, as head of the delegation shares three lesson.
During a recent country visit to Romania, ECDC emphasised the key issues for TB control. Following the invitation of the Romania Ministry of Health, ECDC disease experts, led by ECDC Director Marc Sprenger, visited the Marius Nasta Institute, which historically has been in the front line for TB control in the country.
IGRAs are increasingly being considered for the diagnosis of LTBI, as a replacement to the TST, including travel medicine. As with the TST, many uncertainties remain with regard to the efficacy of the IGRAs. It is therefore essential to secure an accurate understanding of these assays‘ known efficacy, so that they be optimally used and only in context with proven effect.
A new report, Tuberculosis surveillance in Europe 2009, a joint publication from ECDC and the WHO Regional Office for Europe to mark World Tuberculosis Day 2011, provides evidence for concern about the spread of multi-drug resistant tuberculosis (MDR TB) and the persistence of TB among children.