The WHO Regional Committee for Europe approved a new action plan to tackle multi-drug resistant and extensively drug resistant tuberculosis (M/XDR-TB) today. This is another milestone in the European efforts to secure strong tuberculosis prevention and control across the region.
This study describes the outcome of 25 travellers with severe malaria who returned from malaria-endemic regions and were treated at 7 centres in Europe with intravenous artesunate. Among these 25 patients, one child and 24 adults (mean ± SD age 44.1 ± 16.1 years), 10 patients received the dosing regimen for artesunate initially recommended by WHO and 11 received artesunate, 2.4 mg/kg/dose.
During a recent country visit to Romania, ECDC emphasised the key issues for TB control. Following the invitation of the Romania Ministry of Health, ECDC disease experts, led by ECDC Director Marc Sprenger, visited the Marius Nasta Institute, which historically has been in the front line for TB control in the country.
IGRAs are increasingly being considered for the diagnosis of LTBI, as a replacement to the TST, including travel medicine. As with the TST, many uncertainties remain with regard to the efficacy of the IGRAs. It is therefore essential to secure an accurate understanding of these assays‘ known efficacy, so that they be optimally used and only in context with proven effect.
This paper describes the results of an open-label randomized trial, comparing the use of artesunate and quinine for the treatment of severe Plasmodium falciparum malaria in children in 11 African countries.