Mumps Complications and Effects of Mumps Vaccination, England and Wales, 2002–2006Archived
The authors analyzed data from hospital admissions and enhanced mumps surveillance to assess mumps complications during the largest mumps outbreak in England and Wales, 2004–2005, and their association with mumps vaccination. When compared with non-outbreak periods, the outbreak was associated with a clear increase in hospitalized patients with orchitis, meningitis and pancreatitis. Routine mumps surveillance and hospital data showed that 6.1% of mumps patients were hospitalized, 4.4% had orchitis, 0.35% meningitis and 0.33% pancreatitis.
Yung CF, Andrews N, Bukasa A, Brown KE, Ramsay M. EID 2011; 17(4): 661–7
Enhanced surveillance data showed 2.9% of mumps patients were hospitalized, 6.1% had orchitis, 0.3% had meningitis and 0.25% had pancreatitis. Risk was reduced for hospitalization (odds ratio [OR] 0.54, 95% confidence interval [CI] 0.43–0.68), mumps orchitis (OR 0.72, 95% CI 0.56–0.93) and mumps meningitis (OR 0.28, 95% CI 0.14–0.56) for those who had received 1 dose of measles, mumps, and rubella vaccine. The protective effect of vaccination on disease severity is critical in assessing the total effects of current and future mumps control strategies.