Germany has reported an outbreak of carbapenemase-producing (NDM-1 and OXA-48) and colistin-resistant Klebsiella pneumoniae sequence type (ST) 307. As of 21 October 2019, 17 patients in three hospitals and one rehabilitation clinic in Mecklenburg-West Pomerania in north-east Germany have been affected. Six of the 17 cases presented with clinical symptoms of infection, while 11 were identified as be carriers.
This issue covers the period 6-12 October 2019 and includes updates on Ebola virus disease, extensively drug-resistant Klebsiella pneumoniae, West Nile virus, mass gathering monitoring (Japan, Rugby World Cup 2019), Poliomyelitis, Measles, Zika virus disease, seasonal influenza, XDR-Typhoid fever.
In 2017, 8.3% (11 787) of the patients who stayed in intensive-care units (ICUs) for more than two days presented with at least one ICU-acquired healthcare-associated infection (HAI) under surveillance (pneumonia, bloodstream infection, or urinary tract infection).
Carbapenem resistance in Enterobacteriaceae such as Klebsiella pneumoniae and Escherichia coli poses a significant threat to patients and healthcare systems in all European Union/European Economic Area (EU/EEA) countries. Carbapenem-resistant Enterobacteriaceae (CRE) infections are associated with high mortality, primarily due to delays in administration of effective treatment and the limited availability of treatment options.
ECDC is organising a short course on “Control of multidrug-resistant micro-organisms (MDROs) in health care settings”. This training opportunity is addressed at healthcare professionals from European Union (EU) and European Economic Area (EEA) countries with current or future responsibility for the prevention and control of healthcare-associated infections (HAIs) due to MDROs working at national or local level. The course is offered by invitation only and participants are identified through the ECDC Coordinating Competent Bodies.
Data are processed for the conduct of the carbapenem- and/or colistin-resistant Enterobacteriaceae (CCRE) survey as part of molecular surveillance of antimicrobial resistant pathogens according to a protocol. For the CCRE survey bacterial isolates (carbapenem and/or colistin-resistant Enterobacteriaceae and susceptible control isolates) and related patient data are collected in hospitals in 37 countries with the aim to determine transmission pathways and improve control measures.
A large outbreak of New Delhi metallo-beta-lactamase (NDM)-producing carbapenem-resistant Enterobacteriaceae (CRE) has been reported from the Tuscany region in Italy. Between November 2018 and May 2019, seven Tuscan hospitals notified a total of 350 cases.
The EAAD Technical Advisory Committee (TAC) meets once a year to provide technical advice and the strategic direction for EAAD. In 2019 the meeting will be held in Stockholm on 22 - 24 May.